Alternative Lengthening of Telomeres and Chromatin Status

Telomere length is maintained by either telomerase, a reverse transcriptase, or alternative lengthening of telomeres (ALT), a mechanism that utilizes homologous recombination (HR) proteins. Since access to DNA for HR enzymes is regulated by the chromatin status, it is expected that telomere elongati...

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Bibliographic Details
Main Authors: Ion Udroiu, Antonella Sgura
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Genes
Subjects:
alt
Online Access:https://www.mdpi.com/2073-4425/11/1/45