Cytokine production but lack of proliferation in peripheral blood mononuclear cells from chronic Chagas' disease cardiomyopathy patients in response to T. cruzi ribosomal P proteins.

Cytokine production but lack of proliferation in peripheral blood mononuclear cells from chronic Chagas' disease cardiomyopathy patients in response to T. cruzi ribosomal P proteins.

BACKGROUND: Trypanosoma cruzi ribosomal P proteins, P2β and P0, induce high levels of antibodies in patients with chronic Chagas' disease Cardiomyopathy (CCC). It is well known that these antibodies alter the beating rate of cardiomyocytes and provoke apoptosis by their interaction with β1-adre...

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Bibliographic Details
Main Authors: Silvia A Longhi, Augusto Atienza, Graciela Perez Prados, Alcinette Buying, Virginia Balouz, Carlos A Buscaglia, Radleigh Santos, Laura M Tasso, Ricardo Bonato, Pablo Chiale, Clemencia Pinilla, Valeria A Judkowski, Karina A Gómez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4046937?pdf=render

Internet

http://europepmc.org/articles/PMC4046937?pdf=render

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