Ribosomal Protein S6 Kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein

<p>Abstract</p> <p>Background</p> <p>Epithelial to mesenchymal transition (EMT) occurs during cancer cell invasion and malignant metastasis. Features of EMT include spindle-like cell morphology, loss of epithelial cellular markers and gain of mesenchymal phenotype. Acti...

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Bibliographic Details
Main Authors: Zhang Rui-Wen, Zhou Yong-Qing, Padhye Snehal S, Guin Sunny, Ma Qi, Wang Ming-Hai
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/66