Toxic Activity, Molecular Modeling and Docking Simulations of Bacillus thuringiensis Cry11 Toxin Variants Obtained via DNA Shuffling

The Cry11 family belongs to a large group of δ-endotoxins that share three distinct structural domains. Among the dipteran-active toxins referred to as three-domain Cry11 toxins, the Cry11Aa protein from Bacillus thuringiensis subsp. israelensis (Bti) has been the most extensively studied. Despite t...

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Bibliographic Details
Main Authors: Alvaro Mauricio Florez, Miguel Orlando Suarez-Barrera, Gloria M. Morales, Karen Viviana Rivera, Sergio Orduz, Rodrigo Ochoa, Diego Guerra, Carlos Muskus
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02461/full