Generation and evaluation of an IPTG-regulated version of Vav-gene promoter for mouse transgenesis.

Different bacteria-derived systems for regulatable gene expression have been developed for the use in mammalian cells and some were also successfully adopted for in vivo use in vertebrate model organisms. However, certain limitations apply to most of these systems, including leakiness of transgene e...

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Bibliographic Details
Main Authors: Francesca Grespi, Eleonora Ottina, Nikolaos Yannoutsos, Stephan Geley, Andreas Villunger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3061885?pdf=render