Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.

Type 2 diabetes is an increasingly common, serious metabolic disorder with a substantial inherited component. It is characterised by defects in both insulin secretion and action. Progress in identification of specific genetic variants predisposing to the disease has been limited. To complement ongoi...

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Bibliographic Details
Main Authors: Inês Barroso, Jian'an Luan, Rita P S Middelberg, Anne-Helen Harding, Paul W Franks, Rupert W Jakes, D Clayton, Alan J Schafer, Stephen O'Rahilly, Nicholas J Wareham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2003-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0000020