Age-dependent modulation of cortical transcriptomes in spinal cord injury and repair.

Both injury and aging of the central nervous system reportedly produce profound changes in gene expression. Therefore, aging may interfere with the success of therapeutic interventions which were tailored for young patients. Using genome-scale transcriptional profiling, we identified distinct age-de...

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Bibliographic Details
Main Authors: Anne Jaerve, Fabian Kruse, Katharina Malik, Hans-Peter Hartung, Hans Werner Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517588?pdf=render