Multiple Rare Risk Coding Variants in Postsynaptic Density-Related Genes Associated With Schizophrenia Susceptibility

Multiple Rare Risk Coding Variants in Postsynaptic Density-Related Genes Associated With Schizophrenia Susceptibility

ObjectiveSchizophrenia is a chronic debilitating neurobiological disorder of aberrant synaptic connectivity and synaptogenesis. Postsynaptic density (PSD)–related proteins in N-methyl-D-aspartate receptor–postsynaptic signaling complexes are crucial to regulating the synaptic transmission and functi...

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Bibliographic Details
Main Authors: Tsung-Ming Hu, Ying-Chieh Wang, Chia-Liang Wu, Shih-Hsin Hsu, Hsin-Yao Tsai, Min-Chih Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
schizophrenia
PSD gene
resequencing
rare mutation
in vitro
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.524258/full

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https://www.frontiersin.org/articles/10.3389/fgene.2020.524258/full

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