Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges

Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges

Initially believed to be a disease of deregulated cellular and genetic expression, cancer is now also considered a disease of the tumor microenvironment. Over the past two decades, significant and rapid progress has been made to understand the complexity of the tumor microenvironment and its contrib...

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Bibliographic Details
Main Authors: Muhammad Zaeem Noman, Meriem Hasmim, Audrey Lequeux, Malina Xiao, Caroline Duhem, Salem Chouaib, Guy Berchem, Bassam Janji
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
hypoxia
HIF
tumor microenvironment
immune checkpoints
immunotherapy
autophagy
Online Access:https://www.mdpi.com/2073-4409/8/9/1083

Internet

https://www.mdpi.com/2073-4409/8/9/1083

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