SYK Inhibition Potentiates the Effect of Chemotherapeutic Drugs on Neuroblastoma Cells In Vitro

SYK Inhibition Potentiates the Effect of Chemotherapeutic Drugs on Neuroblastoma Cells In Vitro

Neuroblastoma is a malignancy arising from the developing sympathetic nervous system and the most common and deadly cancer of infancy. New therapies are needed to improve the prognosis for high-risk patients and to reduce toxicity and late effects. Spleen tyrosine kinase (SYK) has previously been id...

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Bibliographic Details
Main Authors: Conny Tümmler, Gianina Dumitriu, Malin Wickström, Peter Coopman, Andrey Valkov, Per Kogner, John Inge Johnsen, Ugo Moens, Baldur Sveinbjörnsson
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
pediatric cancer
neuroblastoma
tyrosine kinase
combination therapy
Online Access:https://www.mdpi.com/2072-6694/11/2/202

Internet

https://www.mdpi.com/2072-6694/11/2/202

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