Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma

Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma

Extraskeletal myxoid chondrosarcoma (EMC) is an extremely rare soft tissue sarcoma, marked by a translocation involving the NR4A3 gene. EMC is usually indolent and moderately sensitive to anthracycline-based chemotherapy. Recently, we reported on the therapeutic activity of sunitinib in a series of...

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Bibliographic Details
Main Authors: Milena Urbini, Valentina Indio, Annalisa Astolfi, Giuseppe Tarantino, Salvatore Lorenzo Renne, Silvana Pilotti, Angelo Paolo Dei Tos, Roberta Maestro, Paola Collini, Margherita Nannini, Maristella Saponara, Ludovica Murrone, Gian Paolo Dagrada, Chiara Colombo, Alessandro Gronchi, Andrea Pession, Paolo Giovanni Casali, Silvia Stacchiotti, Maria Abbondanza Pantaleo
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Molecular Sciences
Subjects:
KIT
EMC
extraskeletal myxoid chondrosarcoma
next generation sequencing
Online Access:http://www.mdpi.com/1422-0067/19/7/1855

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http://www.mdpi.com/1422-0067/19/7/1855

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