The glutamate-glutamine(GABA) cycle: importance of late postnatal development and potential reciprocal interactions between biosynthesis and degradation

The glutamate-glutamine(GABA) cycle: importance of late postnatal development and potential reciprocal interactions between biosynthesis and degradation

The gold standard for studies of glutamate-glutamine(GABA) cycling and its connections to brain biosynthesis from glucose of glutamate and GABA and their subsequent metabolism are the elegant in vivo studies by 13C magnetic resonance spectroscopy (NMR), showing the large fluxes in the cycle. However...

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Bibliographic Details
Main Author: Leif eHertz
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Endocrinology
Subjects:
Astrocyte；
Glutamate oxidation；
Glutamine-glutamate(GABA) shuttle；
Glutamine synthetase；
Glycogen；
Learning;
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00059/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00059/full

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