An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria

An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria

Signaling by serine/threonine phosphorylation controls diverse processes in bacteria, and identification of the stimuli that activate protein kinases is an outstanding question in the field. Recently, we showed that nutrients stimulate phosphorylation of the protein kinase G substrate GarA in Mycoba...

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Bibliographic Details
Main Authors: Nabanita Bhattacharyya, Irene Nailain Nkumama, Zaccheus Newland-Smith, Li-Ying Lin, Wen Yin, Rebecca E. Cullen, Jack S. Griffiths, Alexander R. Jarvis, Michael J. Price, Pei Ying Chong, Russell Wallis, Helen M. O’Hare
Format: Article
Language:English
Published: American Society for Microbiology 2018-07-01
Series:mBio
Subjects:
Actinobacteria
Corynebacterium
Mycobacterium tuberculosis
sensory transduction processes
serine/threonine kinases
structural biology
Online Access:https://doi.org/10.1128/mBio.00931-18

Internet

https://doi.org/10.1128/mBio.00931-18

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