The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells.

The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells.

The capacity of a virus to cross species barriers is determined by the development of bona fide interactions with cellular components of new hosts, and in particular its ability to block IFN-α/β antiviral signaling. Tioman virus (TioV), a close relative of mumps virus (MuV), has been isolated in gia...

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Bibliographic Details
Main Authors: Grégory Caignard, Marianne Lucas-Hourani, Kevin P Dhondt, Jean-Louis Labernardière, Thierry Petit, Yves Jacob, Branka Horvat, Frédéric Tangy, Pierre-Olivier Vidalain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544715?pdf=render

Internet

http://europepmc.org/articles/PMC3544715?pdf=render

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