Klotho: its various functions and association with sickle cell disease subphenotypes

The Klotho protein, whose gene has predominant renal expression, acts in the control of serum phosphorus and 1,25-dihydroxyvitamin D3 and regulates the function of ion channels. It also participates in the mechanism of protection against oxidative stress and acts on the vascular endothelium by induc...

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Bibliographic Details
Main Authors: Ana Paula Almeida de Souza Pacheco, Marilda Goncalves
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842014000600430&lng=en&tlng=en