Klotho: its various functions and association with sickle cell disease subphenotypes
The Klotho protein, whose gene has predominant renal expression, acts in the control of serum phosphorus and 1,25-dihydroxyvitamin D3 and regulates the function of ion channels. It also participates in the mechanism of protection against oxidative stress and acts on the vascular endothelium by induc...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
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Series: | Revista Brasileira de Hematologia e Hemoterapia |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842014000600430&lng=en&tlng=en |