Structural cytotoxicity relationship of 2-phenoxy(thiomethyl)pyridotriazolopyrimidines: Quantum chemical calculations and statistical analysis

Previously, a series of pyridotriazolopyrimidines (1–6) were synthesized and fully described. The target compounds (1–6) were evaluated for their cytotoxicity against MCF-7, HepG2, WRL 68, and A549 (breast adenocarcinoma, hepatocellular carcinoma, embryonic liver, and pulmonary adenocarcinoma, respe...

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Bibliographic Details
Main Authors: Abuelizz Hatem A., Anouar El Hassane, Al-Shakliah Nasser S., Marzouk Mohamed, Al-Salahi Rashad
Format: Article
Language:English
Published: De Gruyter 2020-06-01
Series:Open Chemistry
Subjects:
dft
mlr
slr
Online Access:https://doi.org/10.1515/chem-2020-0138