Skewed CD39/CD73/adenosine pathway in B cells is associated with innate immune hyperactivation in chronic HIV-1 infection

Skewed CD39/CD73/adenosine pathway in B cells is associated with innate immune hyperactivation in chronic HIV-1 infection

Abstract Background The CD39/CD73/adenosine suppression pathway correlates with disease progression in patients with chronic human immunodeficiency virus 1 (HIV-1) infection; however, the relationships between this pathway in B cells and innate immune hyperactivation remain largely undefined. Method...

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Bibliographic Details
Main Authors: Wen-Xian Chang, Hui-Huang Huang, Lei Huang, Ji-Jing Shi, Yan-Mei Jiao, Chao Zhang, Lei Jin, Tao Yang, Ming Shi, Bo Tu, Zhe Xu, Tian-Jun Jiang, Fu-Sheng Wang, Ji-Yuan Zhang
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Translational Medicine Communications
Subjects:
Human immunodeficiency virus 1
B cell
CD39
CD73
Immune hyperactivation
Online Access:http://link.springer.com/article/10.1186/s41231-019-0033-8

Internet

http://link.springer.com/article/10.1186/s41231-019-0033-8

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