Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage
Holliday junctions (HJs) are key DNA intermediates in homologous recombination. They link homologous DNA strands and have to be faithfully removed for proper DNA segregation and genome integrity. Here, we present the crystal structure of human HJ resolvase GEN1 complexed with DNA at 3.0 Å resolution...
Main Authors: | Shun-Hsiao Lee, Lissa Nicola Princz, Maren Felizitas Klügel, Bianca Habermann, Boris Pfander, Christian Biertümpfel |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/12256 |
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