Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease during 24 Months of Follow-Up.

Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease during 24 Months of Follow-Up.

Recent findings indicate that microglia in Alzheimer's disease (AD) is senescent whereas peripheral blood mononuclear cells (PBMCs) could infiltrate the brain to phagocyte amyloid deposits. However, the molecular mechanisms involved in the amyloid peptide clearance remain unknown. Autophagy is...

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Bibliographic Details
Main Authors: Arnaud François, Adrien Julian, Stéphanie Ragot, Emilie Dugast, Ludovic Blanchard, Sonia Brishoual, Faraj Terro, Damien Chassaing, Guylène Page, Marc Paccalin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4578953?pdf=render

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http://europepmc.org/articles/PMC4578953?pdf=render

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