Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis

Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis

Regulating dietary fat absorption may impact progression of nonalcoholic fatty liver disease (NAFLD). Here, we asked if inducible inhibition of chylomicron assembly, as observed in intestine-specific microsomal triglyceride (TG) transfer protein knockout mice (Mttp-IKO), could retard NAFLD progressi...

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Bibliographic Details
Main Authors: Yan Xie, Elizabeth P. Newberry, Elizabeth M. Brunt, Samuel J. Ballentine, Saeed Soleymanjahi, Elizabeth A. Molitor, Nicholas O. Davidson
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Lipid Research
Subjects:
intestine
lipid absorption
antioxidant
apolipoprotein B
lipoproteins
microsomal triglyceride transfer protein
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752100105X

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http://www.sciencedirect.com/science/article/pii/S002222752100105X

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