Puzzles in modern biology. IV. Neurodegeneration, localized origin and widespread decay [version 1; referees: 2 approved]
The motor neuron disease amyotrophic lateral sclerosis (ALS) typically begins with localized muscle weakness. Progressive, widespread paralysis often follows over a few years. Does the disease begin with local changes in a small piece of neural tissue and then spread? Or does neural decay happen ind...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2016-10-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/5-2537/v1 |