ACVR1, a Therapeutic Target of Fibrodysplasia Ossificans Progressiva, Is Negatively Regulated by miR-148a

ACVR1, a Therapeutic Target of Fibrodysplasia Ossificans Progressiva, Is Negatively Regulated by miR-148a

Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder of skeletal malformations and progressive extraskeletal ossification. There is still no effective treatment for FOP. All FOP individuals harbor conserved point mutations in ACVR1 gene that are thought to cause ACVR1 constituti...

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Bibliographic Details
Main Authors: Jun Cheng, Deli Zhang, Hao Song, Xuesong Gao, Qi Wang, Junge Wen, Shunai Liu
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:International Journal of Molecular Sciences
Subjects:
ACVR1
miR-148a
FOP
BMP
EndMT
Online Access:http://www.mdpi.com/1422-0067/13/2/2063/

Internet

http://www.mdpi.com/1422-0067/13/2/2063/

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