Sinomenine Hydrochloride Protects against Polymicrobial Sepsis via Autophagy

Sinomenine Hydrochloride Protects against Polymicrobial Sepsis via Autophagy

Sepsis, a systemic inflammatory response to infection, is the major cause of death in intensive care units (ICUs). The mortality rate of sepsis remains high even though the treatment and understanding of sepsis both continue to improve. Sinomenine (SIN) is a natural alkaloid extracted from Chinese...

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Bibliographic Details
Main Authors: Yu Jiang, Min Gao, Wenmei Wang, Yuejiao Lang, Zhongyi Tong, Kangkai Wang, Huali Zhang, Guangwen Chen, Meidong Liu, Yongming Yao, Xianzhong Xiao
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:International Journal of Molecular Sciences
Subjects:
psis
cecal ligation and puncture (CLP)
sinomenine hydrochloride (SIN-HCl)
autophagy
peritoneal macrophages (PM)
Online Access:http://www.mdpi.com/1422-0067/16/2/2559

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http://www.mdpi.com/1422-0067/16/2/2559

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