The Chronotopic™ System for Pulsatile and Colonic Delivery of Active Molecules in the Era of Precision Medicine: Feasibility by 3D Printing via Fused Deposition Modeling (FDM)

The Chronotopic™ System for Pulsatile and Colonic Delivery of Active Molecules in the Era of Precision Medicine: Feasibility by 3D Printing via Fused Deposition Modeling (FDM)

The pulsatile-release Chronotopic™ system was conceived of as a drug-containing core surrounded by a coat made of swellable/soluble hydrophilic polymers, the latter being able to provide a programmable lag phase prior to drug liberation. This system was also proposed in a colon-targeting configurati...

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Bibliographic Details
Main Authors: Alice Melocchi, Marco Uboldi, Francesco Briatico-Vangosa, Saliha Moutaharrik, Matteo Cerea, Anastasia Foppoli, Alessandra Maroni, Luca Palugan, Lucia Zema, Andrea Gazzaniga
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
3D printing
fused deposition modeling
multi-component systems
chronopharmaceutics
controlled release
pulsatile release
Online Access:https://www.mdpi.com/1999-4923/13/5/759

Internet

https://www.mdpi.com/1999-4923/13/5/759

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