Evidence for Arrhythmogenic Effects of A2A-Adenosine Receptors

Evidence for Arrhythmogenic Effects of A2A-Adenosine Receptors

Adenosine can be released from the heart and may stimulate four different cardiac adenosine receptors. A receptor subtype that couples to the generation of cyclic adenosine monophosphate (cAMP) is the A2A-adenosine receptor (A2A-AR). To better understand its role in cardiac function, we studied mech...

Full description

Bibliographic Details
Main Authors: Peter Boknik, Katharina Drzewiecki, John Eskandar, Ulrich Gergs, Britt Hofmann, Hendrik Treede, Stephanie Grote-Wessels, Larissa Fabritz, Paulus Kirchhof, Lisa Fortmüller, Frank Ulrich Müller, Wilhelm Schmitz, Norbert Zimmermann, Uwe Kirchhefer, Joachim Neumann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
A2A-adenosine receptor
contractility
ischemia
reperfusion
arrhythmias
human heart
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01051/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01051/full

Similar Items