Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols

Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols

Abstract Background Master protocols, classified as basket trials, umbrella trials, and platform trials, are novel designs that investigate multiple hypotheses through concurrent sub-studies (e.g., multiple treatments or populations or that allow adding/removing arms during the trial), offering enha...

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Bibliographic Details
Main Authors: Jay J. H Park, Ellie Siden, Michael J. Zoratti, Louis Dron, Ofir Harari, Joel Singer, Richard T. Lester, Kristian Thorlund, Edward J. Mills
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Trials
Subjects:
Master protocols
Basket trials
Umbrella trials
Platform trials
Multi-arm, multi-stage design
Online Access:http://link.springer.com/article/10.1186/s13063-019-3664-1

Internet

http://link.springer.com/article/10.1186/s13063-019-3664-1

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