Cytoplasmic, but not nuclear Nrf2 expression, is associated with inferior survival and relapse rate and response to platinum‐based chemotherapy in non‐small cell lung cancer

Abstract Background Several studies have previously indicated that nuclear factor erythroid 2‐related factor 2 (Nrf2) expression may promote tumor progression when the Keap1/Nrf2 pathway is activated, but few reports have demonstrated the role of cytoplasmic Nrf2 on tumorigenesis. Methods Immunohist...

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Bibliographic Details
Main Authors: Ming‐Jenn Chen, Po‐Lin Lin, Lee Wang, Ya‐Min Cheng, Chih‐Yi Chen, Huei Lee
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Thoracic Cancer
Subjects:
Online Access:https://doi.org/10.1111/1759-7714.13479