Expression Patterns of Immune Genes Reveal Heterogeneous Subtypes of High-Risk Neuroblastoma

Expression Patterns of Immune Genes Reveal Heterogeneous Subtypes of High-Risk Neuroblastoma

High risk neuroblastoma (HR-NB) remains difficult to treat, and its overall survival (OS) is still below 50%. Although HR-NB is a heterogeneous disease, HR-NB patients are currently treated in a similar fashion. Through unsupervised biclustering, we further stratified HR-NB patients into two reprodu...

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Bibliographic Details
Main Authors: Zhenqiu Liu, Christa N. Grant, Lidan Sun, Barbara A. Miller, Vladimir S. Spiegelman, Hong-Gang Wang
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
ultra-high risk neuroblastoma
clinically distinct subtypes
immune-related gene signatures
prognostic markers
biclustering
TP53 signaling
Online Access:https://www.mdpi.com/2072-6694/12/7/1739

Internet

https://www.mdpi.com/2072-6694/12/7/1739

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