Gastrodin Inhibits Store-Operated Ca2+ Entry and Alleviates Cardiac Hypertrophy

Gastrodin Inhibits Store-Operated Ca2+ Entry and Alleviates Cardiac Hypertrophy

Cardiac hypertrophy is a major risk factor for heart failure, which are among the leading causes of human death. Gastrodin is a small molecule that has been used clinically to treat neurological and vascular diseases for many years without safety issues. In the present study, we examined protective...

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Bibliographic Details
Main Authors: Xiaoqiang Yao, Changbo Zheng, Chun-Yin Lo, Zhaoyue Meng, Zhichao Li, Mingkui Zhong, Peng Zhang, Jun Lu, Zhaoxiang Yang, Fuman Yan, Yunting Zhang, Yu Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Pharmacology
Subjects:
gastrodin
hypertrophy
cardiomyocyte
SOCE
STIM1
Orai1
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00222/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00222/full

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