Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells.

Approximately 10-15% of individuals infected with Helicobacter pylori will develop ulcer disease (gastric or duodenal ulcer), while most people infected with H. pylori will be asymptomatic. The majority of infected individuals remain asymptomatic partly due to the inhibition of synthesis of choleste...

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Bibliographic Details
Main Authors: Yuki Ito, Jose Luis Vela, Fumiko Matsumura, Hitomi Hoshino, Aaron Tyznik, Heeseob Lee, Enrico Girardi, Dirk M Zajonc, Robert Liddington, Motohiro Kobayashi, Xingfeng Bao, Jeanna Bugaytsova, Thomas Borén, Rongsheng Jin, Yinong Zong, Peter H Seeberger, Jun Nakayama, Mitchell Kronenberg, Minoru Fukuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3846475?pdf=render