Interplay between matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in acute asthma exacerbation and airway remodeling

Background: Airway inflammation and remodeling of extracellular matrix are important features of asthma. Matrix metalloproteinases (MMPs) are group of enzymes expressed in the airways with their inhibitor (tissue inhibitor of MMPs (TIMP) and they are the key responsible for extra cellular matrix (EC...

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Bibliographic Details
Main Authors: Ghada Mahmoud Mohamed, Mohamed Nazmy Farres, Hala Mahmoud
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-07-01
Series:Egyptian Journal of Chest Disease and Tuberculosis
Subjects:
ECM
Online Access:http://www.sciencedirect.com/science/article/pii/S0422763812000210