Non-Esterified Fatty Acids Over-Activate the TLR2/4-NF-Κb Signaling Pathway to Increase Inflammatory Cytokine Synthesis in Neutrophils from Ketotic Cows

Non-Esterified Fatty Acids Over-Activate the TLR2/4-NF-Κb Signaling Pathway to Increase Inflammatory Cytokine Synthesis in Neutrophils from Ketotic Cows

Background/Aims: Dairy cows with clinical ketosis display a negative energy balance and high blood concentrations of non-esterified fatty acids (NEFAs), the latter of which is an important pathological factor of ketosis in cows. The aims of this study were to investigate the inflammatory status of k...

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Bibliographic Details
Main Authors: Yuming Zhang, Xiaobing Li, Haolong Zhang, Zhibo Zhao, Zhicheng Peng, Zhe Wang, Guowen Liu, Xinwei Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Non-esterified fatty acids
NF-κB signaling pathway
Inflammation
Neutrophils
Online Access:https://www.karger.com/Article/FullText/491913

Internet

https://www.karger.com/Article/FullText/491913

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