Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors

Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors

Summary Introduction: Breast cancer is the most cause of death, and approximately 90% of these deaths are due to metastases. Matrix metalloproteinase-2 (MMP-2) gelatinase activity is able to degrade a major constituent of the tumor microenvironment, type IV collagen. Two well-established proteins u...

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Bibliographic Details
Main Authors: Edneia A. S. Ramos, Camila T. da Silva, Graciele C. M. Manica, Isabela T. Pereira, Liliane M. B. Klassen, Enilze M. S. F. Ribeiro, Iglenir J. Cavalli, Karin Braun-Prado, Rubens S. Lima, Cicero A. Urban, Fabrício F. Costa, Lucia de Noronha, Giseli Klassen
Format: Article
Language:English
Published: Associação Médica Brasileira
Series:Revista da Associação Médica Brasileira
Subjects:
neoplasias da mama
MMP-2
imuno-histoquímica
marcador molecular
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000800774&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000800774&lng=en&tlng=en

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