Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of invasive breast cancer

OBJECTIVE: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the posttranscriptional level. Some miRNAs, including let-7a and miR-195, have been described as tumor suppressors. However, the roles of these microRNAs in breast cancer progression remain controversial. The ai...

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Bibliographic Details
Main Authors: Marcia M. Marques, Adriane F. Evangelista, Taciane Macedo, René Aloisio da Costa Vieira, Cristovam Scapulatempo-Neto, Rui M. Reis, André L. Carvalho, Ismael Dale Cotrim Guerreiro da Silva
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2018-07-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100240&lng=en&tlng=en