Elicitation of Cluster A and Co-Receptor Binding Site Antibodies are Required to Eliminate HIV-1 Infected Cells

Elicitation of Cluster A and Co-Receptor Binding Site Antibodies are Required to Eliminate HIV-1 Infected Cells

HIV-1-infected individuals raise a polyclonal antibody response targeting multiple envelope glycoprotein (Env) epitopes. Interestingly, two classes of non-neutralizing CD4-induced (CD4i) antibodies, present in the majority of HIV-1-infected individuals have been described to mediate antibody-depende...

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Bibliographic Details
Main Authors: Guillaume Beaudoin-Bussières, Jérémie Prévost, Gabrielle Gendron-Lepage, Bruno Melillo, Junhua Chen, Amos B. Smith III, Marzena Pazgier, Andrés Finzi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Microorganisms
Subjects:
HIV-1
ADCC
cluster A
coreceptor binding site
guinea pigs
small CD4 mimetics
Online Access:https://www.mdpi.com/2076-2607/8/5/710

Internet

https://www.mdpi.com/2076-2607/8/5/710

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