Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex

Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex

Abstract Background Histone deacetylase 6 (HDAC6) is a microtubule-associated deacetylase that promotes many cellular processes that lead to cell transformation and tumour development. We previously documented an interaction between Ran-Binding Protein M (RanBPM) and HDAC6 and found that RanBPM expr...

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Bibliographic Details
Main Authors: Louisa M. Salemi, Matthew E. R. Maitland, Eyal R. Yefet, Caroline Schild-Poulter
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cancer
Subjects:
RanBPM
HDAC6
α-tubulin
CTLH complex
Cell migration
Online Access:http://link.springer.com/article/10.1186/s12885-017-3430-2

Internet

http://link.springer.com/article/10.1186/s12885-017-3430-2

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