Iron deficiency negatively regulates protein methylation via the downregulation of protein arginine methyltransferase

Iron is an essential trace metal for all biological processes and plays a role in almost every aspect of body growth. Previously, we found that iron-depletion downregulated the expression of proteins, arginine methyltransferase-1 and 3 (PRMT1 and PRMT3), by an iron-specific chelator, deferoxamine (D...

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Bibliographic Details
Main Authors: Hirofumi Inoue, Nobuaki Hanawa, Shin-Ichi Katsumata, Yumi Aizawa, Rie Katsumata-Tsuboi, Miori Tanaka, Nobuyuki Takahashi, Mariko Uehara
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020319022