Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems

Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems

The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate patient-specific models for the investigation of...

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Bibliographic Details
Main Authors: Marta Trevisan, Alessandro Sinigaglia, Giovanna Desole, Alessandro Berto, Monia Pacenti, Giorgio Palù, Luisa Barzon
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Viruses
Subjects:
human induced pluripotent stem cells
viral infection
patient-specific disease model
genome editing
genetic susceptibility
antiviral resistance
CRISPR/Cas9
personalized therapy
hepatitis C virus
human immunodeficiency virus
Online Access:http://www.mdpi.com/1999-4915/7/7/2800

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http://www.mdpi.com/1999-4915/7/7/2800

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