CD20-Mimotope Peptides: A Model to Define the Molecular Basis of Epitope Spreading

CD20-Mimotope Peptides: A Model to Define the Molecular Basis of Epitope Spreading

Antigen-mimicking peptide (mimotope)-based vaccines are one of the most promising forms of active-immunotherapy. The main drawback of this approach is that it induces antibodies that react poorly with the nominal antigen. The aim of this study was to investigate the molecular basis underlying the we...

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Bibliographic Details
Main Authors: Elvira Favoino, Marcella Prete, Giacomo Catacchio, Giuseppina Conteduca, Federico Perosa
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
mimotope
peptide
active immunotherapy
antigenicity
immunogenicity
epitope spreading
vaccine
CD20
Rituximab
Online Access:https://www.mdpi.com/1422-0067/20/8/1920

Internet

https://www.mdpi.com/1422-0067/20/8/1920

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