Xylo-Oligosaccharides in Prevention of Hepatic Steatosis and Adipose Tissue Inflammation: Associating Taxonomic and Metabolomic Patterns in Fecal Microbiomes with Biclustering

Xylo-Oligosaccharides in Prevention of Hepatic Steatosis and Adipose Tissue Inflammation: Associating Taxonomic and Metabolomic Patterns in Fecal Microbiomes with Biclustering

We have shown that prebiotic xylo-oligosaccharides (XOS) increased beneficial gut microbiota (GM) and prevented high fat diet-induced hepatic steatosis, but the mechanisms associated with these effects are not clear. We studied whether XOS affects adipose tissue inflammation and insulin signaling, a...

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Bibliographic Details
Main Authors: Jukka Hintikka, Sanna Lensu, Elina Mäkinen, Sira Karvinen, Marjaana Honkanen, Jere Lindén, Tim Garrels, Satu Pekkala, Leo Lahti
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Environmental Research and Public Health
Subjects:
non-alcoholic fatty liver disease
xylo-oligosaccharides
metabolites
gut microbiota
biclustering
high fat diet
Online Access:https://www.mdpi.com/1660-4601/18/8/4049

Internet

https://www.mdpi.com/1660-4601/18/8/4049

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