Preparation, Characterization, and In Vivo Pharmacokinetic Study of the Supercritical Fluid-Processed Liposomal Amphotericin B

Preparation, Characterization, and In Vivo Pharmacokinetic Study of the Supercritical Fluid-Processed Liposomal Amphotericin B

Here, we aimed to prepare and optimize liposomal amphotericin B (AmB) while using the supercritical fluid of carbon dioxide (SCF-CO<sub>2</sub>) method and investigate the characteristics and pharmacokinetics of the SCF-CO<sub>2</sub>-processed liposomal AmB. Liposomes contai...

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Bibliographic Details
Main Authors: Chang-baek Lim, Sharif Md Abuzar, Pankaj Ranjan Karn, Wonkyung Cho, Hee Jun Park, Cheong-Weon Cho, Sung-Joo Hwang
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Pharmaceutics
Subjects:
amphotericin b
liposomes
supercritical fluid
hemolysis
ambisome<sup>®</sup>
pharmacokinetic
Online Access:https://www.mdpi.com/1999-4923/11/11/589

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https://www.mdpi.com/1999-4923/11/11/589

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