Chemokine-Releasing Nanoparticles for Manipulation of the Lymph Node Microenvironment

Chemokine-Releasing Nanoparticles for Manipulation of the Lymph Node Microenvironment

Chemokines (CKs) secreted by the host cells into surrounding tissue establish concentration gradients directing the migration of leukocytes. We propose an in vivo CK gradient remodeling approach based on sustained release of CKs by the crosslinked poly(N-isopropylacrylamide) hydrogel open meshwork n...

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Bibliographic Details
Main Authors: Taissia G. Popova, Allison Teunis, Ruben Magni, Alessandra Luchini, Virginia Espina, Lance A. Liotta, Serguei G. Popov
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Nanomaterials
Subjects:
nanoparticles
chemokines
neutrophils
lymph node
Online Access:http://www.mdpi.com/2079-4991/5/1/298

Internet

http://www.mdpi.com/2079-4991/5/1/298

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