Chemokine-Releasing Nanoparticles for Manipulation of the Lymph Node Microenvironment
Chemokines (CKs) secreted by the host cells into surrounding tissue establish concentration gradients directing the migration of leukocytes. We propose an in vivo CK gradient remodeling approach based on sustained release of CKs by the crosslinked poly(N-isopropylacrylamide) hydrogel open meshwork n...
Main Authors: | Taissia G. Popova, Allison Teunis, Ruben Magni, Alessandra Luchini, Virginia Espina, Lance A. Liotta, Serguei G. Popov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-03-01
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Series: | Nanomaterials |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-4991/5/1/298 |
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