Biochemical and biological evaluation of gyroxin isolated from Crotalus durissus terrificus venom

Biochemical and biological evaluation of gyroxin isolated from Crotalus durissus terrificus venom

Gyroxin, a thrombin-like enzyme isolated from Crotalus durissus terrificus venom and capable of converting fibrinogen into fibrin, presents coagulant and neurotoxic activities. The aim of the present study was to evaluate such coagulant and toxic properties. Gyroxin was isolated using only two chrom...

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Bibliographic Details
Main Authors: LC Barros, AM Soares, FL Costa, VM Rodrigues, AL Fuly, JR Giglio, M Gallacci, IA Thomazini-Santos, SRCS Barraviera, B Barraviera, RS Ferreira Junior
Format: Article
Language:English
Published: SciELO 2011-01-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
gyroxin
neurotoxicity
coagulant activity
Crotalus durissus terrificus
serine proteinase
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000100004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000100004

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