Dynein-mediated transport and membrane trafficking control PAR3 polarised distribution

The scaffold protein PAR3 and the kinase PAR1 are essential proteins that control cell polarity. Their precise opposite localisations define plasma membrane domains with specific functions. PAR3 and PAR1 are mutually inhibited by direct or indirect phosphorylations, but their fates once phosphorylat...

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Bibliographic Details
Main Authors: Julie Jouette, Antoine Guichet, Sandra B Claret
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/40212