LncRNA SNHG7 Regulates Mesenchymal Stem Cell Through the Notch1/Jagged1/Hes-1 Signaling Pathway and Influences Folfirinox Resistance in Pancreatic Cancer

LncRNA SNHG7 Regulates Mesenchymal Stem Cell Through the Notch1/Jagged1/Hes-1 Signaling Pathway and Influences Folfirinox Resistance in Pancreatic Cancer

Pancreatic cancer (PC) is one of the deadliest gastrointestinal cancers, accounting for the fourth highest number of cancer-related fatalities. Increasing data suggests that mesenchymal stem cells (MSCs) might influence the drug resistance of GC cells in the tumor microenvironment and play essential...

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Bibliographic Details
Main Authors: Dongfeng Cheng, Juanjuan Fan, Kai Qin, Yiran Zhou, Jingrui Yang, Yang Ma, Minmin Shi, Jiabin Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
SNHG7
Notch1
pancreatic cancer
stemness
resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.719855/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.719855/full

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