Pentaerythritol as an excipient/solid-dispersion carrier for improved solubility and permeability of ursodeoxycholic acid

In this study, the feasibility of using pentaerythritol as a novel excipient/solid-dispersion carrier for enhancing the biopharmaceutical properties of ursodeoxycholic acid (UA) is explored. The solid dispersion formulations of UA were prepared using a solvent evaporation technique. The prepared for...

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Bibliographic Details
Main Authors: Vivek Dave, Darshan Telange, Roshni Denge, Arun Patil, Milind Umekar, Sheeba Varghese Gupta
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council
Series:Journal of Excipients and Food Chemicals
Online Access:http://jefc.scholasticahq.com/article/4708-pentaerythritol-as-an-excipient-solid-dispersion-carrier-for-improved-solubility-and-permeability-of-ursodeoxycholic-acid.pdf