Characterization of SPAD Array for Multifocal High-Content Screening Applications

Characterization of SPAD Array for Multifocal High-Content Screening Applications

Current instruments used to detect specific protein-protein interactions in live cells for applications in high-content screening (HCS) are limited by the time required to measure the lifetime. Here, a 32 × 1 single-photon avalanche diode (SPAD) array was explored as a detector for fluorescence life...

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Bibliographic Details
Main Authors: Anthony Tsikouras, Pietro Peronio, Ivan Rech, Nehad Hirmiz, M. Jamal Deen, Qiyin Fang
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Photonics
Subjects:
single-photon avalanche diode
time-correlated single-photon counting
confocal microscopy
time-resolved imaging
high-content screening
drug discovery
Online Access:http://www.mdpi.com/2304-6732/3/4/56

Internet

http://www.mdpi.com/2304-6732/3/4/56

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