Fentanyl Inhibits Air Puff-Evoked Sensory Information Processing in Mouse Cerebellar Neurons Recorded in vivo

Fentanyl Inhibits Air Puff-Evoked Sensory Information Processing in Mouse Cerebellar Neurons Recorded in vivo

Aim: To examine the effects of fentanyl, a potent mu-opioid receptor (MOR) agonist, on-air puff-evoked responses in Purkinje cells (PCs), and molecular layer interneurons (MLIs) using in vivo patch-clamp recordings in anesthetized mice.Methods: Male mice 6–8 weeks-old were anesthetized and fixed on...

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Bibliographic Details
Main Authors: He-Min Yang, Li-Jie Zhan, Xue-Qin Lin, Chun-Ping Chu, De-Lai Qiu, Yan Lan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Systems Neuroscience
Subjects:
fentanyl
μ-opioid receptor
cerebellar Purkinje cell
molecular layer interneuron
CTOP
protein kinase A
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2020.00051/full

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https://www.frontiersin.org/article/10.3389/fnsys.2020.00051/full

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