Real-time resolution of short-read assembly graph using ONT long reads.

A streaming assembly pipeline utilising real-time Oxford Nanopore Technology (ONT) sequencing data is important for saving sequencing resources and reducing time-to-result. A previous approach implemented in npScarf provided an efficient streaming algorithm for hybrid assembly but was relatively pro...

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Bibliographic Details
Main Authors: Son Hoang Nguyen, Minh Duc Cao, Lachlan J M Coin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008586